EARLY PREGNANCY AND ENDOTHELIAL DYSFUNCTION
نویسندگان
چکیده
منابع مشابه
Endothelial damage/dysfunction and hypertension in pregnancy.
Hypertension is one of the most common medical conditions complicating pregnancy, with significant implications on maternal and perinatal morbidity and mortality. Abnormalities in placentation have been implicated as the primary pathology responsible for the development of hypertension during pregnancy and its effects such as pre-eclampsia and eclampsia. With advancing research, the focus is no...
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Since the discovery in the 1980s that nitric oxide (NO) is in fact the elusive endothelium-derived relaxing factor, it has become evident that NO is not only a major cardiovascular signalling molecule, but that changes in its bioavailability are crucial in determining whether atherosclerosis will develop or not. Sustained high levels of harmful circulating stimuli associated with cardiovascular...
متن کاملVascular adaptation in pregnancy and endothelial dysfunction in preeclampsia.
Maternal vascular adaptation to pregnancy is critically important to expand the capacity for blood flow through the uteroplacental unit to meet the needs of the developing fetus. Failure of the maternal vasculature to properly adapt can result in hypertensive disorders of pregnancy such as preeclampsia (PE). Herein, we review the endocrinology of maternal adaptation to pregnancy and contrast th...
متن کاملEndothelial dysfunction: An early marker for atherosclerosis
Since the 80's, vascular endothelium emerged as a complex, local, regulating system of haemostasis, thrombosis and fibrinolysis, immunity, and vasomotricity. Most vessels (except capillaries) are under control of endothelium/smooth muscle complex (and probably adventitia) which allows local adjustment of calibre, as well as, resistance and distribution of the blood flow to the organs. This loca...
متن کاملAbnormal carbohydrate metabolism during pregnancy : association with endothelial dysfunction.
OBJECTIVE To evaluate whether abnormal endothelial function, a common finding in premenopausal women with type 2 diabetes, is present in early states of diabetes during pregnancy, such as impaired glucose tolerance (IGT) and gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS Brachial artery flow-mediated dilatation (FMD) (endothelium-dependent) and nitrate-induced dilatation (NI...
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ژورنال
عنوان ژورنال: Wiadomości Lekarskie
سال: 2020
ISSN: 0043-5147
DOI: 10.36740/wlek202004122